TABLE OF CONTENTS

Reaction of ferrocene with trichloro-acetimidates in presence of TMSOTf as a catalyst gave a series of novel ferrocenyl compounds 1-7 in good yield and by a simple method using the Friedel-Crafts reaction. The prepared compounds showed medium to good antimicrobial activity against Bacillus subtilis (+ve), Staphylococcus aureus (+ve), Candida albicans (yeast), Esherichia coli (-ve), Salmonella typhi (-ve), Aspergillus niger (fungi) and Fusarium solani (fungi).

Two antibacterial and antifungal ferro-cene-incorporated compounds have been synthesized, characterized and screened for their in vitro antibacterial activity against Escherichia coli,lebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, Salmonella typhi, Shigella dysenteriae, Bacillus cereus, Corynebacterium diphtheriae, Staphylococcus aureus and Streptococcus pyogenes bacterial strains and for in vitro antifungal activity against Trichophyton longifusus, Candida albicans, Aspergillus flavus, Microsporum canis, Fusarium solani and Candida glaberata. The results show that these compounds have significant activity against the tested bacterial and fungal strains and thus introduce a novel class of ferrocene-incorporated antibacterial and antifungal compounds.

Two 4-coordinated titanocene complexes, [(⁵-C₅H₅)₂Ti(O,O')(5-NO₂- OCC₆H₃)] (I) and [(⁵-C₅H₅)₂Ti(2-OH-5-NO₂-O₂CC₆H₃)₂] (II), were synthesized in aqueous media. Single-crystal X-ray analysis determination showed that the dramatic change of conditions has great effect on the molecular structure of 5-nitrosalicylate titanocene, thereby has significant influence on the weak interactions and the specific framework structure.

A new series of homoleptic ruthenium complexes based on 4,4-dialkylaminomethyl-2,2-bipyridine (bpy) ligands has been prepared and their spectroscopy properties have been investigated. The complexes exhibit Ru-to-bpy MLCT absorption centered about 462 nm. Band maxima of metal-to-ligand charge transfer emission of ruthenium complexes were observed at 632, 623 and 638 nm, respectively.

Eight new bridged (cyclopentadienyl)(fluorenyl) complexes were studied on the ethylene and propylene polymerization. The influence of substituents on the bridge carbon on the catalytic activities for ethylene polymerization was insignificant. However, for propylene polymerization, the substituents on phenyl groups of bridge carton affected not only the catalytic activities but also the microstructure and properties of polypropylene.

Group 4 complexes containing diphosphinoamide ligands [Ph₂PNR]₂MCl₂ have been synthesized and characterized, and were shown to be moderately active catalysts for polymerization of ethylene in the presence of modified methylaluminoxane or i-Bu₃Al/Ph₃BC(C₆F₅)₄.

The bis(diorganodithiocarbamato)organodithiocarbonatobismuth(III) complexes of the type [R₂NCS₂]₂BiS₂COR (where, R = Me and Et; R = Et, Prⁿ, Prⁱ, Buⁿ and Buⁱ) have been synthesized and characterized by physico-chemical and spectral [IR, NMR (¹H and ¹³C)] methods.

1

N-(trialkoxysilylalkyl) derivatives of 1,2,3,4-tetrahydroquinoline, 1,2,3,4-tetrahydroisoquinoline and 4,4-dimethyl-4-sila-1,2,3,4-tetrahydroisoquinoline were prepared and characterized by elemental analysis, ¹H, ¹³C and ²⁹Si NMR spectroscopy. In vivo psychotropic properties and in vitro cytotoxic effects of 3-[N-(1,2,3,4-tetrahydroisoquinolyl)]propyltriethoxysilane methiodide and 3-[N-(1,2,3,4-tetrahydroisoquinolyl)]propylsilatrane are reported. Comparative study of ²⁹Si shifts in newly synthesized compounds suggests donor-acceptor interaction between nitrogen and silicon atom, which increases electron density at Si nuclei, revealing a stronger increment of N Si transannular bond in comparison with N Si-effect. The molecular structure of 3-[N-(1,2,3,4-tetrahydroisoquinolyl)]propylsilatrane features a penta-coordinate silicon atom having CSiO₃ pattern and SiN intramolecular interaction.

Silatrane (1) directly synthesized via the oxide one pot synthesis (OOPS) process is used as the precursor to prepare Fe-loaded MFI zeolite via sol-gel process using tetrapropyl ammonium bromide as a template.